In epigenomics, location is everything: Researchers exploit gene position to test 'histone code'
Thursday, January 3, 2013 - 12:20
in Biology & Nature
In a novel use of gene knockout technology, researchers at the University of California, San Diego School of Medicine tested the same gene inserted into 90 different locations in a yeast chromosome – and discovered that while the inserted gene never altered its surrounding chromatin landscape, differences in that immediate landscape measurably affected gene activity.