Scientists study transient degradation of an actin regulator

Scientists at the Center for Molecular Biology of Heidelberg University have gained new insight into the process of mitosis in mammalian cells. Researchers under the direction of Prof. Dr. Frauke Melchior, in collaboration with colleagues from Göttingen, Milan and Memphis, have succeeded in deciphering a heretofore unknown mechanism that plays a key role in cell shape changes during mitosis. They investigated the transient degradation of a protein that regulates specific structures of the mechanical scaffold of the cell, the actin cytoskeleton.

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