Previously unpublished paper by Francis Crick and Jeffries Wyman, "A footnote on allostery"
Thursday, April 18, 2013 - 07:36
in Biology & Nature
It is rare that an unpublished piece of research or theory remains significant after half a century. It is also a wonderful example of the boundless curiosity of the late Francis Crick. A previously unpublished work by Francis Crick and Jeffries Wyman from 1965 is now available, together with Jean-Pierre Changeux's recollections on the origins of the theory of Allostery and several important texts by various authors on the subject. These are part of a special issue of the Journal of Molecular Biology (JMB) published at the occasion of a Pasteur/EMBO Conference on Allosteric Interactions in Cell Signaling and Regulation to be held at the Pasteur Institute in Paris, May 14-17, 2013, to mark a half-century of research on this subject.