Large-scale screen reveals how numerous signaling pathways intersect at the cell's primary protein-processing center

Many proteins undergo extensive modification after being synthesized, particularly those that are secreted or embedded in the cell membrane. This is achieved within the Golgi apparatus (see image), a cellular organelle consisting of multiple membrane-bound compartments known as cisternae. Each of these contains specific sets of protein-modifying enzymes, which sequentially modify their targets. For example, many proteins undergo glycosylation, which entails the stepwise addition of complex sugar molecules.

Read the whole article on Physorg

More from Physorg