Longevity mutation found in flies far and wide

Wednesday, February 5, 2014 - 13:10 in Biology & Nature

For years, researchers have been investigating how mutations of a gene called Indy (for "I'm Not Dead Yet") affect metabolism, life span, and reproductive fitness in both mammals and fruit flies. So far mutations in Indy have been studied experimentally only in the lab. No longer. A new study reports that a particularly important variation of the gene with much the same life-governing consequences has actually been widespread among fruit flies, judging by lines gathered from the wild across the entire globe for 60 years.

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