Pattern of brain-specific protein modifications is driven by the regulation of multiple enzymes
Friday, May 2, 2014 - 08:01
in Biology & Nature
(Phys.org) —Many human proteins are modified by the attachment of short sugar chains called glycans. The patterns of attachment, or glycosylations, are known to be specific to organs, tissues and cell types, but the mechanisms regulating these patterns have been unclear. Naoyuki Taniguchi, Yasuhiko Kizuka and colleagues from the RIKEN–Max Planck Joint Research Center for Systems Chemical Biology have now clarified one such mechanism in the brain.