Regulation of developmental gene expression occurs in the reverse order to that expected

Friday, July 18, 2014 - 07:00 in Biology & Nature

Molecular modification of DNA and the histone proteins it is bound to is one of the key mechanisms responsible for regulating gene expression. Polycomb-group proteins play an important role in some of these modification processes, but the molecular mechanisms by which they bind to DNA and exert their effects have been poorly understood.

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