Researchers create first inhibitor for enzyme linked to cancers

Thursday, November 20, 2014 - 17:30 in Health & Medicine

Recent studies showing acid ceramidase (AC) to be upregulated in melanoma, lung and prostate cancers have made the enzyme a desired target for novel synthetic inhibitor compounds. This week in Angewandte Chemie, a top journal in chemistry, UC Irvine and Italian Institute of Technology scientists describe the very first class of AC inhibitors that may aid in the efficacy of chemotherapies.

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