Cells repair damaged DNA by a different mechanism than assumed

Defects in DNA can cause serious harm to an organism, including cell death or the development of cancer. Efficient repair mechanisms are therefore of vital importance. LMU chemist Professor Christian Ochsenfeld, Chair of Theoretical Chemistry at LMU, and Dr. Keyarash Sadeghian from his group have explained for the first time in detail how a human DNA repair enzyme works. Their computer simulations show that the repair process is different from what was previously thought. The scientists have reported their results in the current issue of the Journal of the American Chemical Society.

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