Synthetic strategy for enantioselective aldol reactions with fluoroacetate
Wednesday, January 27, 2016 - 09:23
in Biology & Nature
(Phys.org)—Fluorine, the most electronegative atom on the periodic table, has some interesting applications in organic and medicinal chemistry. Replacing hydrogen with fluorine can often boost biological activity and carbon-fluorine bonds are strong enough to withstand metabolic conditions. To that end, many scientists are interested in making fluorinated derivatives of pharmaceuticals. Unfortunately, it is difficult to functionalize certain organic compounds with fluorine.
