Modified form of CRISPR acts as a toggle switch to control gene expression in stem cells
Thursday, March 10, 2016 - 12:00
in Biology & Nature
Combining the two most powerful biological tools of the 21st century, scientists at the Gladstone Institutes have modified how the genome of induced pluripotent stem cells (iPSCs) is read for the first time using a variation of the CRISPR-Cas9 system. The development offers a major technological advance in creating cell models of genetic diseases.