Study links developmental and lipid handling pathways in C. elegans

A Massachusetts General Hospital (MGH) research team reports finding that a previously unknown interaction between metabolic pathways in two different tissues within the C.elegans roundworm triggers a key step in maturation. In their report published in Genes & Development, the investigators describe finding how microRNAs in the skin of the roundworm, which are known to control the animals' transition through key developmental stages, link to a signaling pathway that directs the transport of lipids from storage in the intestine to reproductive cells for support of embryonic growth.

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