Novel method enables absolute quantification of mitochondrial metabolites

Wednesday, August 31, 2016 - 13:31 in Physics & Chemistry

Whitehead Institute scientists have developed a method to quickly isolate and systematically measure metabolite concentrations within the cellular organelles known as mitochondria, often referred to as the "powerhouses of the cell." Prior attempts at such measurements have yielded unreliable results, either by taking too long to isolate mitochondria or by contaminating mitochondrial metabolites with contents from other cellular components.

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