Scientists discover interplay of yin-yang antagonists vital for cell division

How a cell transitions from the G1 phase of the cell cycle to the S phase – a fundamental process of cell division for all eukaryotic cells on Earth – has been a long-studied question in biology. Now UNC School of Medicine scientists discovered that this boundary is regulated by a pair of large enzyme complexes that attack each other in turn to form a molecular switch, which eventually allows the cell cycle to enter into S phase.

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