Systems biology study discovers proteins that become more stable with increasing age

Thursday, October 6, 2016 - 12:22 in Biology & Nature

Some proteins behave in an unusual way: the older they become, the longer their life expectancy. A research team at the Max Delbrück Center in the Helmholtz Association (MDC) has now published this paradoxical finding in the journal Cell. Their work has traced the life cycle of thousands of molecules from the translation of mRNA transcripts to the disposal of the proteins they encode. The results are relevant for diseases where there are surplus copies of certain genes.

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