New catalytic asymmetric reaction directly installs amines into carbonyl compounds
Tuesday, November 22, 2016 - 09:31
in Physics & Chemistry
A team of organic chemists at ITbM, Nagoya University, has developed a new reaction to directly install amines into carbonyl compounds using their unique phase-transfer catalyst. This unprecedented method leads to the rapid formation of optically active (chiral) α-aminocarbonyls, which are structural moieties found in many biologically active compounds and in therapeutics, such as anti-malarial and anti-HIV agents.
