Directed evolution to design enzymes that make imaging agents for medical diagnosis
Wednesday, May 31, 2017 - 07:02
in Physics & Chemistry
Organic molecules containing a fluorine atom are widely used in the materials, agrochemical and pharmaceutical industries. However, synthesizing the carbon-fluorine bond typically utilizes toxic metal catalysts and requires anhydrous conditions and high temperatures. Now an international team has developed a milder, more efficient enzyme-based approach to create this bond.