The arrestin-GPCR connection
Monday, April 15, 2019 - 06:50
in Biology & Nature
G-protein coupled receptors (GPCRs) are the "inbox" of environmental messages in mammalian cells. Because of their central role in signaling pathways, mutations resulting in abnormal GPCR functions cause a wide variety of diseases. Therefore, GPCRs are the most intensively studied drug targets.