Scientists investigate radiolabeling of calcium carbonate particles in vivo
Tuesday, July 14, 2020 - 10:40
in Physics & Chemistry
Сalcium carbonate particles are among the most promising bioactive compounds. However, before their use for drug delivery, their toxicity should be established, as well as their distribution inside laboratory animals. A team of investigators from ITMO University's Department of Physics and Engineering and Russian Scientific Center of Radiology and Surgical Technologies has developed novel approaches to load calcium carbonate particles with model radionuclides and studied the biodistribution of these particles on rats using positron emission tomography (PET). They found that the size of the particles influences the specific organ accumulation in vivo. The results of this study are published in ACS Applied Materials and Interfaces.