Recombinant and tunable spidroin hydrogels for drug release and cell culture

Friday, June 2, 2023 - 11:53 in Biology & Nature

In a new study, researchers at Karolinska Institutet show that recombinant spider silk protein hydrogels have many attractive features. They allow encapsulation of cells and bioactive molecules simply by incubation at 37°C. They are transparent, which allows monitoring of encapsulated cells, and the fibrillar network mimics that of the extracellular matrix. The mechanical properties of these hydrogels match those of different tissues, and the gels can be used for continuous drug release.

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