IBM Creates DNA-Sequencing Microchips In Race To The $1000 Genome

Tuesday, October 6, 2009 - 13:14 in Biology & Nature

Like many other aspects of health care, the implementation of personal genetic medicine has run aground against the costs of producing an entire genome. Even now, a decade after the completion of the Human Genome Project, commercial whole genome sequencing can cost as much as $100,000. And at that price, the sequencing just isn't worth the benefits. But IBM hopes to change all that. IBM scientists have developed what they call a "DNA transistor". The transistor is a tube only a couple of atoms in diameter that pulls the DNA through, while sensors in the walls of the tube read the base pairs. This process simulates natural protein pores in cells that evolve specifically to read DNA strands. By running an entire genome through the tube, IBM hopes to lower the cost of sequencing an entire genome down to $1,000. IBM, best known as...

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