Penn biologists discover how 'silent' mutations influence protein production
Friday, April 10, 2009 - 08:49
in Biology & Nature
Biologists at the University of Pennsylvania have revealed a hidden code that determines the expression level of a gene, providing a way to distinguish efficient genes from inefficient ones. The new research, which involved creating hundreds of synthetic green-glowing genes, provides an explanation for how a cell 'knows' how much of each protein to make, providing just the right amount of protein to maintain homeostasis yet not too much to cause cell toxicity...