Investigating the development of mechanosensitivity

Researchers of the Max Delbrueck Centre for Molecular Medicine (MDC) Berlin-Buch, Germany, have gained crucial insight into how mechanosensitivity arises. By measuring electrical impulses in the sensory neurones of mice, the neurobiologists and pain researchers Dr Stefan G. Lechner and Professor Gary Lewin were able to directly elucidate, for the first time, the emergence of mechanosensitivity. At the same time they were able to show that neurones develop their sensitivity to touch and pain during different developmental phases but always coincidentally with the growth of the neuronal pathways...

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