Immune cells predict outcome of West Nile virus infection

Infection with West Nile virus (WNV) causes no symptoms in most people. However, it can cause fever, meningitis, and/or encephalitis. What determines the outcome of infection with WNV in different people has not been determined. But now, Philip Norris and colleagues, at the Blood Systems Research Institute, San Francisco, have found that levels of immune cells known as Tregs (immune cells that suppress the function of other immune cells) in the blood of a human or mouse infected with WNV predict whether the person or mouse will have symptoms of infection...

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