Getting on 'the GABA receptor shuttle' to treat anxiety disorders

Friday, October 23, 2009 - 08:07 in Biology & Nature

There are increasingly precise molecular insights into ways that stress exposure leads to fear and through which fear extinction resolves these fear states. Extinction is generally regarded as new inhibitory learning, but where the inhibition originates from remains to be determined. Gamma-aminobutyric acid (GABA), the primary inhibitory chemical messenger in the brain, seems to be very important to these processes...

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