Researchers 'notch' a victory toward new kind of cancer drug

Scientists have devised an innovative way to disarm a key protein considered to be 'undruggable,' meaning that all previous efforts to develop a drug against it have failed. Their discovery, published in the November 12 issue of Nature, lays the foundation for a new kind of therapy aimed directly at a critical human protein - one of a few thousand so-called transcription factors - that could someday be used to treat a variety of diseases, especially multiple types of cancer...

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