Studies shed new light on early transmembrane signalling

Two new studies by researchers at the University of Washington further our understanding of the molecular steps in the PLC cascade, a G protein-coupled receptor signalling mechanism that underlies a wide variety of cellular processes, including egg fertilisation, hormone secretion, and the regulation of certain potassium channels. The studies appear online January 25 in the Journal of General Physiology (www.jgp.org)...

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