Study finds epigenetic similarities between Wilms tumour cells and normal kidney stem cells

A detailed analysis of the epigenetics - factors controlling when and in what tissues genes are expressed - of Wilms tumour reveals striking similarities to stem cells normally found in foetal kidneys. These findings by Massachusetts General Hospital (MGH) Cancer Centre researchers have revealed new cellular pathways that are critical for Wilms tumour development and may also apply to other paediatric cancers. The report appears in the June 4 Cell Stem Cell...

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