Study sheds light on cancer-causing gene regulation

Tuesday, August 17, 2010 - 05:07 in Health & Medicine

Researchers at Beth Israel Deaconess Medical Centre (BIDMC) have uncovered the genes that regulate MDM2, an oncogene that, in turn, regulates the tumour suppressor protein p53. But instead of an on-off switch for MDM2, the team found what looks like a dimmer switch, suggesting a more complicated signalling pathway that is sensitive to a changing environment...

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