Unsung hero: Researchers produce high-res model of Ndc80 in action

Unless you are in a field of study related to cell biology, you most likely have never heard of Ndc80. Yet this protein complex is essential to mitosis, the process by which a living cell separates its chromosomes and distributes them equally between its two daughter cells. Now, through a combination of cryo-electron microscopy and three-dimensional image reconstruction, a team of researchers with the Lawrence Berkeley National Laboratory and the University of California (UC) Berkeley have produced a subnanometre resolution model of human Ndc80 that reveals how this unsung hero carries out its essential tasks...

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