Psychotic-like symptoms associated with poor outcomes in patients with depression

Tuesday, December 7, 2010 - 12:10 in Health & Medicine

Among patients with depression, the presence of many aspects of illness which may be associated with bipolar disorder does not appear to be associated with treatment resistance - evidence against the common hypothesis that some cases of difficult-to-treat depression are actually unrecognised bipolar disorder, according to a report posted online today that will appear in the April 2011 print issue of Archives of General Psychiatry, one of the JAMA/Archives journals. However, many patients with depression also report psychotic-like symptoms, such as hearing voices or believing they are being spied on or plotted against, and those who do are less likely to respond to treatment...

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