Cell reprogramming leaves a 'footprint' behind

Thursday, February 3, 2011 - 13:20 in Biology & Nature

Reprogramming adult cells to recapture their youthful 'can-do-it-all' attitude appears to leave an indelible mark, found researchers at the Salk Institute for Biological Studies. When the team, led by Joseph Ecker, PhD., a professor in the Genomic Analysis Laboratory, scoured the epigenomes of so-called induced pluripotent stem cells base by base, they found a consistent pattern of reprogramming errors...

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