14 Drugs Identified As Most Urgently Needing Study For Off-label Use

Physicians and policy-makers know that drugs are frequently prescribed to treat certain diseases despite a lack of FDA approval, a practice known as off-label prescribing. Now researchers have developed a list of 14 widely prescribed medications most urgently in need of additional study to determine how effective and safe they are for their off-label uses. Antidepressants and antipsychotics are the most prominent classes of drugs on the list.

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