Long-term Treatment With Proton Pump Inhibitor Can Increase Weight

A clinical research team from Japan examined the effects of long-term proton pump inhibitor (PPI) therapy on body weight (BW) and body mass index in patients with gastroesophageal reflux disease (GERD). They concluded long-term PPI treatment was associated with BW gain in patients with GERD. Reflux patients receiving PPI should be encouraged to manage BW through lifestyle modifications.

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