Genetic analysis helps dissect molecular basis of cardiovascular disease

Using highly precise measurements of plasma lipoprotein concentrations determined by nuclear magnetic resonance spectroscopy, researchers performed genetic association analysis across the whole genome among 17,296 women of European ancestry. This large scale analysis of the effects of common genetic variation on plasma lipoprotein profile, a critical component of cardiovascular risk, identified 43 genetic loci contributing to lipoprotein metabolism.

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