Is nicotinamide overload a trigger for type 2 diabetes?

Type 2 diabetes is a major global health problem. Although the underlying mechanism of the pathogenesis is not clear, generally it is accepted that type 2 diabetes is a result of gene-environment interactions. A research group from China investigated the relationship between the metabolism of nicotinamide and diabetes and found that nicotinamide overload may be involved in the development of diabetes.

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