What it might take to unravel the 'lean mean machine' that is cancer

Tuesday, February 23, 2010 - 23:21 in Biology & Nature

Scientists in Australia have published a new paper describing gene expression in a prostate cancer cell: more sweeping, more targeted and more complex than we could ever have imagined, even five years ago. The study shows that changes within the prostate cancer cell "epigenome" (biochemical processes that target DNA and affect gene expression) alter the expression of many genes, silencing their expression within large regions of DNA -- nearly 3 percent of the cell's genome.

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