Cancer cells show rewired, fragmented microRNA networks

Monday, May 3, 2010 - 17:40 in Biology & Nature

A new study shows that in healthy cells molecules of microRNA work together in single, well-connected networks that resemble a family tree with dozens to hundreds of members. In cancer cells, however, the networks are rewired and fragmented, with small detached clusters. The research introduces a new way of discovering cancer genes and identifies new microRNAs that can be used as targets for drug development and pinpoints possible new cancer-related proteins.

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