Surprise in genome structure linked to developmental diseases

The genes that are responsible for maintaining each cell type form DNA loops that link control elements for these genes. The DNA loop structure is essential for regulating the activity of cell-type-specific genes and thus maintaining cell state. Problems with the loop structure can cause multiple syndromes and diseases, including Opitz-Kaveggia syndrome, Lujan syndrome, schizophrenia and Cornelia de Lange syndrome.

Read the whole article on Science Daily

More from Science Daily