Malaria research begins to bite: Molecular switches pinpointed in control of malaria parasite's life cycle
Monday, October 25, 2010 - 00:31
in Biology & Nature
Scientists have pin-pointed the 72 molecular switches that control the three key stages in the life cycle of the malaria parasite and have discovered that over a third of these switches can be disrupted in some way. Their research is a significant breakthrough in the search for cheap and effective vaccines and drugs to stop the transmission of a disease which kills up to a million children a year. Until now little has been known about the cellular processes involved in the development of this deadly disease. The research involved the very first comprehensive functional analysis of protein kinases in any malaria parasite. It is also the largest gene knock-out study in Plasmodium berghei -- a malaria parasite infecting rodents.