Recombination hotspot stacks the DNA deck in finding a new diabetes susceptibility gene

Type 1 diabetes (T1D) is diagnosed in approximately 70,000 children worldwide per year. Genetics is recognized as playing a significant role in susceptibility to T1D, but outside a handful of genes, a clear understanding of the genetic architecture that underlies T1D has remained elusive. In a new study, scientists have identified a novel gene associated with diabetes in mice, revealing new clues about genomic mechanisms that could underlie T1D susceptibility.

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