Structure of Lassa virus protein reveals viral thievery

Wednesday, November 17, 2010 - 22:30 in Biology & Nature

Scientists have solved the structure of a key protein from Lassa virus, which is endemic to West Africa and can cause a deadly hemorrhagic fever. The structure reveals how the virus evades its host's immune system, and how it hijacks infected cells' vital machinery in a process scientists call "cap-stealing." Details of the structure could guide future efforts at antiviral drug discovery and vaccine development.

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