Duchenne muscular dystrophy is ultimately a stem cell disease

Thursday, December 9, 2010 - 13:30 in Biology & Nature

For years, scientists have tried to understand why children with Duchenne muscular dystrophy experience severe muscle wasting and eventual death. After all, laboratory mice with the same mutation that causes the disease in humans display only a slight weakness. Now new research and a new animal model of the disease, points a finger squarely at the inability of human muscle stem cells to keep up with the ongoing damage caused by the disorder.

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