New method powerfully boosts efficiency of RNA interference (RNAi) in shutting down genes

Scientists have developed a powerful method that allows them to sift through thousands of candidate hairpin-shaped RNA molecules at a time and pull out only those RNAs that potently shut down the activity of a target gene. This accomplishment will now allow biologists to fully exploit RNA interference, a natural cellular mechanism that has already been co-opted by scientists for myriad purposes.

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