Can diabetes or lipid-lowering medications treat addiction?

Thiazolidinediones (TZDs) are commonly prescribed to treat Type 2 diabetes, while fibrates are prescribed to modulate lipid levels in patients to help reduce the risk of cardiovascular disease. These drugs work by binding to peroxisome proliferator-activated receptors (PPARs). Another effect of TZDs and fibrates is to raise leptin levels, an effect that may reduce appetite.

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