Neural guidance gene regulates liver development

Scientists have demonstrated for the first time that a gene regulating neuronal cell migration during embryogenesis also plays a role in liver development. Using zebrafish as a model organism, they showed that the gene navigator-3 (nav3a) regulates liver organogenesis. If nav3a is missing, the liver cannot develop. First evidence indicates that the expression of this gene is deregulated during the pathogenesis of liver diseases in humans.

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