Scientists identify a surprising new source of cancer stem cells

Monday, April 11, 2011 - 23:30 in Biology & Nature

Certain differentiated cells in breast tissue can spontaneously convert to a stem-cell-like state, according to Whitehead Institute researchers. Until now, scientific dogma has stated that differentiation is a one-way path; once cells specialize, they cannot return to the flexible stem-cell state on their own. These findings hold true for normal mammary cells as well as for breast cancer cells.

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