Inverting a standard experiment sometimes produces different results
Thursday, April 28, 2011 - 15:31
in Physics & Chemistry
The standard experimental setup for measuring the cellular uptake of nanoparticles is to place cells in a well on a culture plate and cover them with culture medium containing nanoparticles. The assumption underlying these experiments is that the particles remain well-dispersed. But when a scientist turned cell cultures upside down, he discovered that this assumption doesn't always hold. Some experiments preparing for the clinical use of nanoparticles may therefore need to be redone.