Neuroscientists' discovery could bring relief to epilepsy sufferers; Computational model of epileptic seizures at molecular level

Researchers have made a discovery that could help drug manufacturers develop new antiepileptic drugs and explore novel strategies for treating seizures associated with epilepsy. The researchers used a computational model of the cortical network to show that during seizure there is a slow and progressive buildup of intracellular sodium in neurons, and that it is this accumulation of intracellular sodium that leads to the termination of the seizure.

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