Fight against sepsis: Fibrin, a product of the blood clotting process, is key to protection during gram-negative sepsis

Monday, July 11, 2011 - 12:30 in Health & Medicine

New research may help to explain why anticoagulant therapies have largely failed to extend the lives of patients with sepsis. The study shows that fibrin, a key product of the blood clotting process, is critical for host defense against Yersinia enterocolitica, a gram-negative bacterium that causes sepsis in humans and experimental mice.

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